Advances in Protein Chemistry and Structural Biology: Volume 80 Contributor(s): Donev, Rossen (Editor) |
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ISBN: 012381264X ISBN-13: 9780123812643 Publisher: Academic Press OUR PRICE: $171.00 Product Type: Hardcover - Other Formats Published: December 2010 |
Additional Information |
BISAC Categories: - Science | Life Sciences - Molecular Biology - Science | Life Sciences - Biochemistry - Science | Life Sciences - Biophysics |
Dewey: 547.75 |
Series: Advances in Protein Chemistry and Structural Biology |
Physical Information: 296 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. |