| Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy: Vo Contributor(s): Sosnik, Alejandro, Bendayan, Reina |
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ISBN: 0128164344 ISBN-13: 9780128164341 Publisher: Academic Press OUR PRICE: $157.50 Product Type: Hardcover Published: November 2019 |
| Additional Information |
| BISAC Categories: - Business & Economics | Industries - Pharmaceutical & Biotechnology - Medical | Biotechnology - Medical | Oncology - General |
| Dewey: 616.994 |
| LCCN: 2019946399 |
| Series: Cancer Sensitizing Agents for Chemotherapy |
| Physical Information: 394 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers. The book is a valuable source for researchers and advanced students in cancer, biology, pharmacology, pharmaceutical sciences, biomaterials and medical/clinical sciences that are interested in accessing a comprehensive compendium on efflux pumps in mechanisms of cancer resistance. |