Herpesviruses and Immunity 2002 Edition Contributor(s): Medveczky, Peter G. (Editor), Friedman, Herman (Editor), Bendinelli, Mauro (Editor) |
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ISBN: 030645890X ISBN-13: 9780306458903 Publisher: Springer OUR PRICE: $161.49 Product Type: Hardcover - Other Formats Published: October 1998 Annotation: The remarkable ability of herpesviruses to escape immunity brings together the two disciplines of immunology and virology in an inextricable way. Because herpesvirus can induce, suppress, and fool the immune system, the most productive herpesvirologists are also expert immunologists, and the results of this latest interdisciplinary effort document the interactions between both disciplines. Herpesviruses and Immunity brings together the contributions of world-class herpesvirus virologists and immunologists who summarize their work to recount some of the most exciting current developments in the field of herpes virology. |
Additional Information |
BISAC Categories: - Science | Life Sciences - Biology - Medical | Infectious Diseases - Medical | Immunology |
Dewey: 579.243 |
LCCN: 98042559 |
Series: Infectious Agents and Pathogenesis |
Physical Information: 0.94" H x 6" W x 9" (1.50 lbs) 317 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Although virology and immunology are now considered separate disciplines, history shows that these areas ofinvestigation always overlapped and one cannot really exist without the other. This trend has become particularly significant and fruitful in the past few years in the area of herpesvirus research. The genomes of the most important herpesviruses have been sequenced, a significant portion of their genes have been identified, and many secrets of regulation of gene expr- sion have been unraveled. Now this progress sets the stage for a true revolution in herpesvirus research: analysis of interactions between the host and the virus. Because herpesviruses can induce, suppress, and fool the immune system, the most productive herpesvirologists are also expert immunologists, and the current results ofthis interdisciplinary effort are truly remarkable. Because herpesviruses cause many important human diseases, the devel- ment of vaccines against these agents is a very significant goal. This effort is also very challenging because of the complexity of herpesviruses and the lack of sufficient information about immune responses. The remarkable ability of herpesviruses to escape immune responses is - other feature that brings immunology and virology together. Herpesviruses - code many proteins that interact with and down-regulate some key elements of the immune system. Thisproperty of herpesviruses represents amajor challenge in developing strategies against these viruses. On the positive side, these viral proteins also provide novel tools for analyzing specific immune reactions and molecular mechanisms. |