| Synthetic DNA Delivery Systems 2003 Edition Contributor(s): Luo, Dan (Editor), Saltzman, W. Mark (Editor) |
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ISBN: 0306477017 ISBN-13: 9780306477010 Publisher: Springer OUR PRICE: $161.49 Product Type: Hardcover Published: September 2003 Annotation: DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function. Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest. Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic. |
| Additional Information |
| BISAC Categories: - Science | Biotechnology - Science | Life Sciences - Biochemistry - Nature | Plants - Trees |
| Dewey: 660.65 |
| LCCN: 2002043446 |
| Series: Biotechnology Intelligence Unit |
| Physical Information: 0.57" H x 6" W x 9.5" (0.81 lbs) 135 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function. Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest. Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic. |