β-Carbolines: A Privileged Scaffold for Modern Drug Discovery Contributor(s): Ameta Ph. D., K. L. (Editor) |
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ISBN: 1138482382 ISBN-13: 9781138482388 Publisher: CRC Press OUR PRICE: $209.00 Product Type: Hardcover - Other Formats Published: October 2024 This item may be ordered no more than 25 days prior to its publication date of October 8, 2024 |
Additional Information |
BISAC Categories: - Medical | Pharmacy - Science | Chemistry - Organic |
Physical Information: 328 pages |
Descriptions, Reviews, Etc. |
Publisher Description: β-Carboline and its derivatives have generated considerable interest in recent years for their versatile properties in chemistry and pharmacology. This is due to their ability to act as agonists to benzodiazepine receptors, hydroxy serotonin receptors, and intercalate into DNA, to inhibit CDK, Topisomerase, and monoamine oxidase enzymes. Their pharmacological properties include anxiolytic, hypnotic, anticonvulsant, antiviral, antiparasitic and antimicrobial attributes. This book provides a summary of methods for the synthesis of various natural products engineered with the diverse β-carboline scaffold and their biological evaluation. |