| Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications Contributor(s): Tracey, Alan S. (Author), Willsky, Gail R. (Author), Takeuchi, Esther S. (Author) |
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ISBN: 1420046136 ISBN-13: 9781420046137 Publisher: CRC Press OUR PRICE: $228.00 Product Type: Hardcover Published: March 2007 Annotation: Written by leading authorities, this unique work examines the aqueous chemistry of vanadium. Focusing on the V(V) oxidation state, it highlights the use of 51V NMR spectroscopy. It covers reactions of vanadium with biologically important ligands such as amino acids, peptides, and sulfhydryl ligands. It reviews vanadium??'s role in biological systems and pharmacological effects and addresses the importance of ligand electronic properties in determining speciation, coordination geometry, and heteroligand reactivity. It also describes recent advances in practical applications such as in the non-aqueous vanadium oxide bronze battery systems, which are particularly suited to medical applications. |
| Additional Information |
| BISAC Categories: - Science | Chemistry - Inorganic - Medical | Biochemistry |
| Dewey: 546.522 |
| LCCN: 2006028775 |
| Physical Information: 0.79" H x 6.27" W x 9.47" (1.11 lbs) 264 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: The first comprehensive resource on the chemistry of vanadium, Vanadium: Chemistry, Biochemistry, Pharmacology, and Practical Applications has evolved from over a quarter century of research that concentrated on delineating the aqueous coordination reactions that characterize the vanadium(V) oxidation state. The authors distill information on biological processes needed to understand vanadium effects in biological systems and make this information accessible to a wide range of readers, including chemists without extensive biological training. Building a hierarchy of complexity, the book provides a discussion of some basic principles of 51V NMR spectroscopy followed by a description of the self-condensation reactions of vanadate itself. The authors delineate reactions with simple monodentate ligands and then proceed to more complicated systems such as diols, a-hydroxy acids, amino acids, peptides, to name just a few. They revisit aspects of this sequence later, but first highlight the influence the electronic properties of ligands have on coordination and reactivity. They then compare and contrast the influences of ligands, particularly those of hydrogen peroxide and hydroxylamine, on heteroligand reactivity. The book includes coverage of vanadium-dependent haloperoxidases and model systems, vanadium in the environment, and technological applications. It also briefly covers the catalytic reactions of peroxovanadate and haloperoxidase model compounds. It contains a discussion of the vanadium haloperoxidases and the biological and biochemical activities of vanadium(V) including potential pharmacological applications. The last chapters step outside these boundaries by introducing some aspects of the future of vanadium in nanotechnology, the recyclable redox battery, and the lithium/silver vanadium oxide battery. Primary sources documented after each chapter minimize the need to search the literature, 80 illustrations provide structural information, reaction schemes, spectra, speciation diagrams, and biochemical schemes, and 22 tables present detailed information with references to primary sources. Packed with current and authoritative information, the book covers chemistry and bioinorganic vanadium chemistry in a broad and systematic manner that engenders comprehensive understanding. |