| Chiral Recognition and Separation Mechanisms Contributor(s): Grinberg, Nelu (Author), Haddad, Nizar (Author), Ma, Shengli (Author) |
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ISBN: 143985257X ISBN-13: 9781439852576 Publisher: CRC Press OUR PRICE: $189.95 Product Type: Hardcover Published: May 2025 This item may be ordered no more than 25 days prior to its publication date of May 15, 2025 |
| Additional Information |
| BISAC Categories: - Medical | Pharmacy - Science | Chemistry - Industrial & Technical - Science | Research & Methodology |
| Series: Chromatographic Science |
| Physical Information: 350 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Chirality plays a major role in biological processes and the enantiomers of a bioactive molecule often possess different biological effects. Accurate assessment is critical as isomeric impurities may have unwanted toxicological, pharmacological, or other effects. Separation techniques remain the method of choice for this area of drug research but there is a great deal of trial and error in choosing a particular column for a chiral separation. This book gives a rationale for choosing a stationary phase that is based on the relationship that exists between the analytes and the chiral stationary phases. The text provides examples to underline the separation mechanism. |