| Advances in DNA Repair in Cancer Therapy 2013 Edition Contributor(s): Panasci, Lawrence (Editor), Aloyz, Raquel (Editor), Alaoui-Jamali, Moulay (Editor) |
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ISBN: 1461447402 ISBN-13: 9781461447405 Publisher: Humana OUR PRICE: $208.99 Product Type: Hardcover - Other Formats Published: December 2012 |
| Additional Information |
| BISAC Categories: - Science | Life Sciences - Molecular Biology - Medical | Oncology - General - Medical | Research |
| Dewey: 616.994 |
| LCCN: 2012952084 |
| Series: Cancer Drug Discovery & Development |
| Physical Information: 0.9" H x 6.2" W x 9.2" (1.45 lbs) 312 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK. The book captures-for both cancer researchers and oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies. |