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Recent advancement in genome technology, especially high throughput low cost sequencing and microarrays, revolutionizes the way for discovering genetic markers and enables their new applications. This volume is designed to build a genetic tool box with these emerging techniques for molecular biologists, geneticists, clinical scientists and breeders. While theses methods and protocols were developed in genomics and bioinformatics laboratories in the forefront of the fields, the format of each method or protocol is easy to understand and practical to address different challenging issues in genetic marker discovery.