| DNA Repair in Cancer Therapy Contributor(s): Panasci, Lawrence C. (Editor), Alaoui-Jamali, Moulay A. (Editor) |
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ISBN: 1617374806 ISBN-13: 9781617374807 Publisher: Humana OUR PRICE: $161.49 Product Type: Paperback - Other Formats Published: November 2010 |
| Additional Information |
| BISAC Categories: - Medical | Nursing - Oncology & Cancer - Medical | Oncology - General |
| Dewey: 616.994 |
| Series: Cancer Drug Discovery & Development |
| Physical Information: 0.84" H x 6" W x 9" (1.21 lbs) 363 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies. |