Cytomegaloviruses: Molecular Biology and Immunology Contributor(s): Reddehase, Matthias J. (Editor) |
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ISBN: 1904455026 ISBN-13: 9781904455028 Publisher: Caister Academic Press Limited OUR PRICE: $237.50 Product Type: Hardcover Published: January 2006 Annotation: Cytomegaloviruses are members of the herpesvirus group and can infect humans and other primates. Between 50-80% of adults in developed countries and up to 100% in developing countries are infected with human cytomegalovirus. Infection causes problems in immunocompromised hosts including AIDS victims or patients undergoing organ and stem cell transplantation and congenital infection can cause birth defects in the child. Development of an effective vaccine has high priority. In this book, leading international experts provide comprehensive and authoritative reviews on every aspect of current research. By integrating viral genomics, proteomics, immunology, and molecular biology with the emerging knowledge of the genomics of the host organism, penetrating new insights into the virus-host interaction are provided. The focus of the book is on the molecular and genomic aspects and the authors provide an insight into the current understanding of the subject and the future direction of research |
Additional Information |
BISAC Categories: - Medical | Diagnosis - Science | Life Sciences - Molecular Biology |
Dewey: 616.075 |
LCCN: 2007530548 |
Physical Information: 1.4" H x 6.4" W x 9.4" (2.95 lbs) 648 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Cytomegaloviruses are members of the herpesvirus group and can infect humans and other primates. Between 50-80% of adults in developed countries and up to 100% in developing countries are infected with human cytomegalovirus. Infection causes problems in immunocompromised hosts including AIDS victims or patients undergoing organ and stem cell transplantation and congenital infection can cause birth defects in the child. Development of an effective vaccine has high priority. In this book leading international experts provide comprehensive and authoritative reviews on every aspect of current research. By integrating viral genomics, proteomics, immunology and molecular biology with the emerging knowledge of the genomics of the host organism, penetrating new insights into the virus-host interaction are provided. The focus of the book is on the molecular and genomic aspects and the authors provide an insight into the current understanding of the subject and the future direction of research. Topics covered include disease mechanisms, genomics, proteomics, BAC mutagenesis, virus entry and activation of innate immunity, regulation of viral gene expression, regulation of viral mRNA export, animal models of infection, novel therapeutics, vaccine development, antivirals, and much more. The book is liberally illustrated with many figures in full colour and is set is a clear, easy-to-follow layout. Essential reading for all virologists with an interest in cytomegaloviruses and a recommended text for scientists working on antiviral drug and vaccine development. |