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A magnificently reported and soulfully crafted exploration of the human immune system-the key to health and wellness, life and death. An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.

"An Elegant Defense by Matt Richtel is one of those rare nonfiction books that transcends the genre. On one level it is a fascinating and engrossing account of the latest, and quite astonishing, discoveries involving the human immune system and how it works. But it is also a story about people facing mortality, about the passion of scientists searching for truth, and a meditation on death and how all of us struggle with the ultimate mystery. Heartfelt and moving, full of compassion, love, and the human drama, this is the work of a writer of high ethical character who is grappling with big issues and deep humanistic problems. What an inspiring and wonderful read. I highly recommend this extraordinary book." --DOUGLAS PRESTON, #1 bestselling author of The Lost City of the Monkey God

Fred Sanders, an actor and Earphones Award-winning narrator, has received critics' praise for his audio narrations that range from nonfiction, memoir, and fiction to mystery and suspense. He been seen on Broadway in The Buddy Holly Story, in national tours for Driving Miss Daisy and Big River, and on such television shows as Seinfeld, The West Wing, Will and Grace, Numb3rs, Titus, and Malcolm in the Middle. His films include Sea of Love, The Shadow, and the Oscar-nominated short Culture. He is a native New Yorker and Yale graduate.

Matt Richtel is a Pulitzer Prize-winning New York Times reporter and bestselling nonfiction and mystery author. He lives in San Francisco with his wife, Meredith, a neurologist, and their two children. In his spare time, he plays tennis and piano and writes (not very good) songs. Visit him online at www.mattrichtel.wordpress.com.