| Analysis of Human Genetic Linkage Contributor(s): Ott, Jurg (Author) |
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ISBN: 0801861403 ISBN-13: 9780801861406 Publisher: Johns Hopkins University Press OUR PRICE: $95.95 Product Type: Hardcover Published: April 1999 Annotation: The first and still the only book of its kind, this volume offers a concise introduction to human genetic linkage analysis and gene mapping. Jurg Ott provides mathematical and statistical foundations of linkage analysis for researchers and practitioners, as well as practical comments on available computer programs and websites. Each chapter ends with a set of problems, whose solutions are found at the end of the book. New to this edition is a chapter on complex traits, such as diabetes, some cancers, and psychiatric conditions. Also new is an overview of nonparametric approaches to linkage and association analysis. A chapter on two-locus inheritance introduces the reader to many of the intricate aspects of complex traits. Although the book's primary audience is in the field of genetics, physicians and others without sophisticated training in genetics can understand and apply the principles and techniques discussed. Praise for the previous edition: "Overall the book achieves an excellent compromise between presenting important conclusions and working out the details... Analysis of Human Genetic Linkage is a good book that has been made substantially better. It continues to be the standard reference for every linkage analyst's library and to provide an excellent introduction for the interested beginner with a background in the biological or mathematical sciences."--American Journal of Human Genetics |
| Additional Information |
| BISAC Categories: - Medical | Genetics |
| Dewey: 599.935 |
| LCCN: 98-37347 |
| Physical Information: 1.45" H x 6.32" W x 9.26" (1.64 lbs) 416 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: The first and still the only book of its kind, this volume offers a concise introduction to human genetic linkage analysis and gene mapping. Jurg Ott provides mathematical and statistical foundations of linkage analysis for researchers and practitioners, as well as practical comments on available computer programs and websites. Each chapter ends with a set of problems, whose solutions are found at the end of the book. New to this edition is a chapter on complex traits, such as diabetes, some cancers, and psychiatric conditions. Also new is an overview of nonparametric approaches to linkage and association analysis. A chapter on two-locus inheritance introduces the reader to many of the intricate aspects of complex traits. Although the book's primary audience is in the field of genetics, physicians and others without sophisticated training in genetics can understand and apply the principles and techniques discussed. |
Contributor Bio(s): Ott, Jurg: - Jurg Ott is a professor and head of the Laboratory of Statistical Genetics at Rockefeller University. He is editor-in-chief of Human Heredity and the author of the first generally available computer program on human linkage analysis (LIPED). |