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Techniques in Free Radical Research: Volume 22
Contributor(s): Diplock, A. T. (Author), Symons, M. C. R. (Author), Rice-Evans, C. a. (Author)
ISBN: 0444813144     ISBN-13: 9780444813145
Publisher: Elsevier Science
OUR PRICE:   $76.18  
Product Type: Paperback
Published: December 1991
Qty:
Annotation: Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage.


Techniques in Free Radical Research assembles and critically assesses the most relevant and reliable experimental approaches used towards the measurement of radicals and radical-mediated damage in chemical systems, in cells and in tissues under the following six headings: a) Footprints of DNA damage, b) Footprints of protein damage, c) Footprints of lipid peroxidation, d) Footprints of antioxidant consumption, e) Footprints via indirect radical assays, and f) Footprints via the availability of transition metal complexes.
Additional Information
BISAC Categories:
- Medical | Biochemistry
- Science | Life Sciences - Biochemistry
- Science | Life Sciences - Molecular Biology
Dewey: 574.192
LCCN: 85647011
Series: Laboratory Techniques in Biochemistry and Molecular Biology
Physical Information: 0.65" H x 5" W x 8" (0.67 lbs) 290 pages
 
Descriptions, Reviews, Etc.
Publisher Description:

Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or FOOTPRINTS of radical-mediated damage.

Techniques in Free Radical Research assembles and critically assesses the most relevant and reliable experimental approaches used towards the measurement of radicals and radical-mediated damage in chemical systems, in cells and in tissues under the following six headings: a) Footprints of DNA damage, b) Footprints of protein damage, c) Footprints of lipid peroxidation, d) Footprints of antioxidant consumption, e) Footprints via indirect radical assays, and f) Footprints via the availability of transition metal complexes.