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Gerd: Reflux to Esophageal Adenocarcinoma
Contributor(s): Chandrasoma, Parakrama T. (Author), Demeester, Tom R. (Author)
ISBN: 0123694167     ISBN-13: 9780123694164
Publisher: Elsevier Science
OUR PRICE:   $132.05  
Product Type: Hardcover - Other Formats
Published: September 2006
Qty:
Temporarily out of stock - Will ship within 2 to 5 weeks
Annotation: The increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area. GERD brings together, for the first time, a vast amount of disparate literature and documents the entire pathogenesis of reflux disease in one place. The book presents reflux carditis as a new diagnostic criterion of GERD and for the first time defines the dilated end-stage esophagus and the earliest microscopic phase of GERD that is missed by present diagnostic criteria. GERD presents both clinical and pathological information and is meant to be used as a comprehensive reference for gastroenterologists, esophageal surgeons, and pathologists alike.
*Outlines how gastroesophageal reflux causes cellular changes in the esophagus
*Brings together the pathogenesis of the disease in one source and applies it toward clinical treatment
*Tom DeMeester is THE leading international expert on reflux disease; Parakrama Chandrasoma is one of the leading pathologists in the area
*Book contains approximately 350 illustrations
*Ancillary web site features color illustrations: www.chandrasoma.com
Additional Information
BISAC Categories:
- Medical | Pathology
- Science | Life Sciences - Anatomy & Physiology
- Medical | Gastroenterology
Dewey: 616.324
LCCN: 2006284316
Physical Information: 0.9" H x 8.72" W x 11.08" (2.94 lbs) 464 pages
 
Descriptions, Reviews, Etc.
Publisher Description:
Gastroesophageal Reflux Disease (GERD) is one of the most common maladies of mankind. Approximately 40% of the adult population of the USA suffers from significant heartburn and the numerous antacids advertised incessantly on national television represents a $8 billion per year drug market. The ability to control acid secretion with the increasingly effective acid-suppressive agents such as the H2 blockers (pepcid, zantac) and proton pump inhibitors (nexium, prevacid) has given physicians an excellent method of treating the symptoms of acid reflux.

Unfortunately, this has not eradicated reflux disease. It has just changed its nature. While heartburn, ulceration and strictures have become rare, reflux-induced adenocarcinoma of the esophagus is becoming increasingly common. Adenocarcinoma of the esophagus and gastric cardia is now the most rapidly increasing cancer type in the Western world.

The increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area. GERD brings together a vast amount of disparate literature and presents the entire pathogenesis of reflux disease in one place. In addition to providing a new concept of how gastroesophageal reflux causes cellular changes in the esophagus, GERD also offers a complete solution to a problem that has confused physicians for over a century. Both clinical and pathological information about reflux disease and its treatment are presented. GERD is meant to be used as a comprehensive reference for gastroenterologists, esophageal surgeons, and pathologists alike.