| Gabab Receptor Pharmacology: A Tribute to Norman Bowery: Volume 58 Contributor(s): Blackburn, Thomas P. |
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ISBN: 0123786479 ISBN-13: 9780123786470 Publisher: Academic Press OUR PRICE: $256.50 Product Type: Hardcover - Other Formats Published: August 2010 |
| Additional Information |
| BISAC Categories: - Medical | Pharmacology - Medical | Neuroscience - Science | Life Sciences - Neuroscience |
| Dewey: 615 |
| Series: Advances in Pharmacology |
| Physical Information: 1" H x 6.2" W x 9.2" (1.80 lbs) 520 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational, in the discovery of drugs acting at the GABAB receptor. The topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse. The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular. |