Measurement and Analysis of Kinetic Isotope Effects: Volume 596 Contributor(s): Harris, Michael E., Anderson, Vernon |
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ISBN: 0128122730 ISBN-13: 9780128122730 Publisher: Academic Press OUR PRICE: $189.05 Product Type: Hardcover Published: September 2017 |
Additional Information |
BISAC Categories: - Medical - Science | Life Sciences - Biochemistry - Science | Life Sciences - Molecular Biology |
Series: Methods in Enzymology |
Physical Information: 632 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this comprehensive update include Measurement of enzyme binding isotope effects, Chemical ligation and isotope labeling to locate dynamic effects, Measurement of heavy enzyme isotope effects, Extracting kinetic isotope effects from a global analysis of reaction progress curves, KIE of metabolic flux and enzymes, Solvent and Primary KIE on Flavin Enzymes, and The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD. Readers who are interested in applying or understanding this research will find useful methods currently used for measuring isotope effects on solution and enzyme reactions. |