| Studies in Natural Products Chemistry: Stereoselective Synthesis Volume 12 Contributor(s): Rahman, Atta-Ur (Editor) |
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ISBN: 0444893660 ISBN-13: 9780444893666 Publisher: Elsevier OUR PRICE: $589.05 Product Type: Hardcover - Other Formats Published: October 1993 |
| Additional Information |
| BISAC Categories: - Science | Chemistry - Organic - Science | Life Sciences - Biochemistry - Science | Chemistry - Inorganic |
| Dewey: 547.7 |
| LCCN: 88011188 |
| Series: Studies in Natural Products Chemistry |
| Physical Information: 1.19" H x 6" W x 9" (1.96 lbs) 548 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines. Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound. The complete synthesis of erythromycin A is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an A-Ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes. The book can provide useful information to chemists, biologists, students, and researchers. |
