Evaluation of Drug Candidates for Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology Contributor(s): Han, Chao (Editor), Davis, Charles B. (Editor), Wang, Binghe (Editor) |
|
![]() |
ISBN: 0470044918 ISBN-13: 9780470044919 Publisher: Wiley OUR PRICE: $136.75 Product Type: Hardcover - Other Formats Published: January 2010 |
Additional Information |
BISAC Categories: - Medical | Pharmacology - Medical | Pharmacy |
Dewey: 615.19 |
LCCN: 2009035876 |
Series: Wiley Series in Drug Discovery and Development |
Physical Information: 0.8" H x 6.1" W x 9.3" (1.23 lbs) 304 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the "right" drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds. Now, Evaluation of Drug Candidates for Preclinical Development provides a complete view and understanding of why absorption-distribution-metabolism-excretion-toxicology (ADMET) plays a pivotal role in drug discovery and development. Encompassing the three major interrelated areas in which optimization and evaluation of drug developability is most critical--pharmacokinetics and drug metabolism, pharmaceutics, and safety assessment--this unique resource encourages integrated thinking in drug discovery. The contributors to this volume:
Evaluation of Drug Candidates for Preclinical Development serves as an introductory reference for those new to the pharmaceutical industry and drug discovery in particular. It is especially well suited for scientists and management teams in small- to mid-sized pharmaceutical companies, as well as academic researchers and graduate students concerned with the practical aspects related to the evaluation of drug developability. |