Transcription Factors: Normal and Malignant Development of Blood Cells Contributor(s): Ravid, Katya (Editor), Licht, Jonathan D. (Editor) |
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ISBN: 0471350540 ISBN-13: 9780471350545 Publisher: Wiley-Liss OUR PRICE: $326.75 Product Type: Hardcover - Other Formats Published: December 2000 Annotation: Transcription Factors Normal and Malignant Development of Blood Cells Katya Ravid and Jonathan Licht The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias. This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as:
Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and shedslight on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation. |
Additional Information |
BISAC Categories: - Science | Life Sciences - Molecular Biology - Medical | Physiology |
Dewey: 612.11 |
LCCN: 00033018 |
Physical Information: 1.35" H x 7.36" W x 10.2" (2.92 lbs) 640 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Es war schon lange berf llig: Ein topaktuelles Buch ber Transkriptionsfaktoren. Transcription Factors informiert Sie umfassend ber den neuesten Stand der Forschung auf dem Gebiet der experimentellen H matologie und der Biologie der Transkriptionsfaktoren. Geschrieben von anerkannten Experten auf diesem Gebiet. (12/00) |