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Analytical Methods in Combinatorial Chemistry
Contributor(s): Yan, Bing (Author), Zhang, Bin (Author)
ISBN: 0849318602     ISBN-13: 9780849318603
Publisher: CRC Press
OUR PRICE:   $266.00  
Product Type: Hardcover - Other Formats
Published: August 2010
Qty:
Temporarily out of stock - Will ship within 2 to 5 weeks
Annotation: Written by leaders in the field, Analytical Methods in Combinatorial Chemistry is the first comprehensive review of analytical methods in this field, with a focus on combinatorial drug discovery. The second edition updates the first with close to 50% new material and a detailed discussion of new developments in analytical methods, technologies, and applications in combinatorial chemistry in the past three years. The book also includes new chapters on high-throughput purification and the application of combinatorial chemistry in materials science and catalyst discovery. It focuses on new drug candidates and drugs developed through combinatorial chemistry.
Additional Information
BISAC Categories:
- Science | Chemistry - Analytic
- Science | Chemistry - Organic
- Medical | Pharmacy
Dewey: 615.19
LCCN: 2010004973
Series: Critical Reviews in Combinatorial Chemistry
Physical Information: 0.9" H x 6.3" W x 9.3" (1.19 lbs) 238 pages
 
Descriptions, Reviews, Etc.
Publisher Description:

Since the publication of the benchmark first edition of this book, chemical library and combinatorial chemistry methods have developed into mature technologies. There have also been significant shifts in emphasis in combinatorial synthesis. Reflecting the growth in the field and the heightened focus on select areas, Analytical Methods in Combinatorial Chemistry, Second Edition updates a classic text and captures the current state of these technologies.

Written by leaders in the field, this second edition includes several enhancements. A chapter on high-throughput analytical methods and informatics reflects the demand for quality control of library members. A new chapter focuses on high-throughput purification methods. All chapters have been updated with new data.

Topics discussed in this second edition include:

  • Properties of solid-phase samples, analytical studies targeted to understand these properties, and resin swelling
  • Fourier Transform Infrared techniques
  • On-support mass spectrometry and nuclear magnetic resonance methods used in the reaction optimization stage
  • Combinatorial library analysis using spectrophotometric, fluorometric, and other methods
  • Quality control of combinatorial libraries
  • High-throughput purification methods
  • Future directions and analytical challenges

The coming decade is sure to usher in a new wave of progress in this critical field. This volume provides not only an analysis of the recent developments in analytical methods, technologies and applications; it also provides a window on future possibilities.