| Xenobiotic Metabolism and Disposition: The Design of Studies on Novel Compounds Contributor(s): Illing, Harry P. a. (Author) |
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ISBN: 084936163X ISBN-13: 9780849361630 Publisher: CRC Press OUR PRICE: $396.00 Product Type: Hardcover - Other Formats Published: February 1989 |
| Additional Information |
| BISAC Categories: - Medical | Toxicology - Nature | Animals - Mammals - Medical | Pharmacology |
| Dewey: 599.019 |
| LCCN: 88010571 |
| Physical Information: 232 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: This publication explains the principles of the techniques used in disposition and metabolism studies in animals, in man, and in vitro. It includes methods for studying routes and rates of absorption, distribution, metabolism, and excretion of novel compounds and their metabolites. Relevant surgical, whole-body autoradiographic and pharmacokinetic procedures are discussed, together with techniques for separating and identifying metabolites and metabolic path-ways. Information on when the procedures are appropriate, and examples of what they represent, are presented in order to illustrate the value of such studies. |