| Neurobiology of the Trace Amines: Analytical, Physiological, Pharmacological, Behavioral, and Clinical Aspects 1984 Edition Contributor(s): Boulton, Alan A. (Editor), Baker, Glen B. (Editor), Dewhurst, William G. (Editor) |
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ISBN: 0896030636 ISBN-13: 9780896030633 Publisher: Humana OUR PRICE: $208.99 Product Type: Hardcover - Other Formats Published: April 1984 |
| Additional Information |
| BISAC Categories: - Medical | Pain Medicine - Medical | Neuroscience - Science | Life Sciences - Biochemistry |
| Dewey: 615.78 |
| LCCN: 84000626 |
| Series: Polymer Science and Technology |
| Physical Information: 1.31" H x 6.14" W x 9.21" (2.29 lbs) 598 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Many of the trace amines-more correctly called biogenic amines- have been known for decades, but because of their tiny concentra- tions (0. 01-100 ng/g) in brain, it was only after the development of sophisticated analytical techniques (such as mass spectrometry) that they could be identified and quantitated in nervous tissue. There are now more than 20 of them and most are related to the catecholamines and 5-hydroxytryptamine both structurally and metabolically. Their pharmacological and physiological properties make them prime candidates for a transmitter or neuromodulator role and many of them elicit profound behavioral syndromes after injection--one of them, phenylethylamine, has even been referred to as nature's amphetamine. In the clinical sphere several have been shown to be involved in: Parkinsonism, schizophrenia, depression, agoraphobia, aggression, hyperkinesis, migraine, hypertensive crises, hypertyrosinemia, he- patic encephalopathy, epilepsy, and cystic fibrosis. Thus the research reported here on these intriguing "new" substances will be of great interest to psychiatrists, neurologists, biochemists, pharmacologists, physiologists, psychologists, behaviorists and indeed to all those working in the neurosciences and related fields today. ACKNOWLEDGMENTS This book is based on the proceedings of Trace Amines and the Neurosciences, a meeting held at the University of Alberta, Edmonton, July 19-21, 1983. This meeting was organized as a Satellite Meeting of the Ninth Meeting of the International Society for Neurochemistry, held in Vancouver, July 10-15, 1983. International organizers of the satellite meeting were Drs. A. A. Boulton (Saskatoon), W. G. Dewhurst (Edmonton), G. B. Baker (Edmonton), and M. Sandler (London). |
