Iron Metabolism: From Molecular Mechanisms to Clinical Consequences Contributor(s): Crichton, Robert (Author) |
|
![]() |
ISBN: 1118925610 ISBN-13: 9781118925614 Publisher: Wiley OUR PRICE: $203.25 Product Type: Hardcover - Other Formats Published: May 2016 |
Additional Information |
BISAC Categories: - Medical | Endocrinology & Metabolism - Medical | Physiology |
Dewey: 612.392 |
LCCN: 2016012933 |
Physical Information: 1.2" H x 7.4" W x 9.7" (3.00 lbs) 576 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. |