| Microbiological Organic Chemistry: Useful Oxidoreductive Steroid Biotransformations Contributor(s): White, Michael J. (Author) |
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ISBN: 1119136601 ISBN-13: 9781119136606 Publisher: Wiley OUR PRICE: $185.25 Product Type: Hardcover - Other Formats Published: June 2019 |
| Additional Information |
| BISAC Categories: - Science | Chemistry - Organic - Science | Life Sciences - Biochemistry - Science | Life Sciences - Microbiology |
| Physical Information: 400 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: This book discusses the past several decades' advances in microbiological oxidoreductive steroid chemistry, giving a convenient reference and resource for synthetic-steroid chemists and microbiologists working in the area of steroid biotransformations. The author highlights the significant advances that have been made to a powerful technology for the construction of steroids. An introductory chapter reviews the significance of microbiological steroid chemistry, giving examples of how steroid-biotransformation steps have been integrated into drug-product syntheses. The next chapter is dedicated to advances in genetically modified microorganisms, bacteria and fungi, capable of steroid oxidation and reduction; followed by another detailing the use of microbiological steroid chemistry to synthesize and study steroid-drug metabolites. Lastly, the book details numerous examples of steroid biotransformations - cataloging site-specific microbiological steroid oxidations and reductions using either naturally occurring, or genetically modified microorganisms. |