Polycystic Kidney Disease Contributor(s): Hu, Jinghua (Author), Yu, Yong (Author) |
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ISBN: 1138603899 ISBN-13: 9781138603899 Publisher: CRC Press OUR PRICE: $133.00 Product Type: Hardcover - Other Formats Published: November 2019 |
Additional Information |
BISAC Categories: - Medical | Endocrinology & Metabolism - Medical | Nephrology - Science | Life Sciences - Cell Biology |
Dewey: 616.610 |
LCCN: 2019028679 |
Series: Methods in Signal Transduction |
Physical Information: 1" H x 6.4" W x 9.4" (1.65 lbs) 360 pages |
Descriptions, Reviews, Etc. |
Publisher Description: This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies. Key Features
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