| Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders: Novel Strategies for Research and Treatment Contributor(s): Weizman, Abraham (Editor) |
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ISBN: 1402068530 ISBN-13: 9781402068539 Publisher: Springer OUR PRICE: $208.99 Product Type: Hardcover - Other Formats Published: February 2008 Annotation: This book provides a comprehensive and up-to-date overview of the role of neurosteroids and neuroactive steroids, such as pregnenolone and dehydroepiandrosterone, allopregnanolone, progesterone and others in the regulation of brain processes and neuropsychiatric disorders. The book addresses the neurosteroid function in brain development and plasticity, in both the normal and the pathological brain including the aging brain, cognitive functioning, response to stress, anxiety and mood disorders, schizophrenia, and Alzheimer's disease. It also suggests possible therapeutic approaches to the use of natural occurring or sinthetic neurosteroids. The contributors are known experts who suggest that neuroactive steroids could have a role in clinical practice. This book offers a comprehensive, state-of-the-art review of these important bioactive molecules that is relevant to a broad readership which includes neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students in neuroscience, and health care providers in the field of mental health and neurology. |
| Additional Information |
| BISAC Categories: - Medical | Neuroscience - Medical | Psychiatry - General - Medical | Laboratory Medicine |
| Dewey: 155.7 |
| LCCN: 2008920052 |
| Physical Information: 1" H x 6.2" W x 9.3" (2.38 lbs) 559 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Over the past few decades the involvement of neurosteroids in brain function and mental health has attracted much interest, not only from a neuroscience perspective, but also from clinical and therapeutic aspects. In recent years, much of the research has focused on the multifunctional position of neurosteroids in the nervous system. The areas that have been explored, in particular, are the cellular and molecular mechanisms involved in the activity of neurosteroids in the brain, the role of neurosteroids in brain development, neurodegeneration and neuroplasticity, and their pharmacological properties. The large increase in the number of publications highlights this amplified interest in neurosteroids. Over the last 7 years at least 400 papers have been published describing the putative role of neurosteroids in the modulation of basic brain function and in the etiology and treatment of psychiatric and neurological disorders. Contributors to this book are amongst the most active basic researchers and c- nicians in the field and provide new perspectives not only clarifying some of the ongoing controversies, but also proposing diverse aspects and new insights. The book is organized in two major sections: "Neuroactive steroids and brain function', and 'Neuroactive steroids and neuropsychiatric disorders". Though the selection of topics has been influenced by the current state of the art and the issues that require further elaboration, one should not assume that these are the only significant issues at this time. |