| Developmental Toxicology Contributor(s): Hansen, Deborah K. (Author), Abbott, Barbara D. (Author) |
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ISBN: 1420054376 ISBN-13: 9781420054378 Publisher: CRC Press OUR PRICE: $218.50 Product Type: Hardcover Published: October 2008 Annotation: Reflecting the numerous changes in the field since the publication of the previous edition, this third edition of Developmental Toxicology focuses on the mechanisms of developmental toxicity and incorporates current technologies for testing in the risk assessment process. It examines the role of computer modeling and bioinformatics, exploring how these areas can contribute to further understanding the overall process of development. The text also provides complete coverage of such topics as the role of apoptosis, cell-to-cell interactions, the importance of signal transduction, the use of stem cells and zebra fish, as well as whole animal toxicity testing systems. |
| Additional Information |
| BISAC Categories: - Medical | Toxicology - Medical | Perinatology & Neonatology - Medical | Reproductive Medicine & Technology |
| Dewey: 618.32 |
| LCCN: 2008026172 |
| Series: Target Organ Toxicology |
| Physical Information: 0.9" H x 6.1" W x 9.1" (1.45 lbs) 408 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Highlighting latest advances in genetics and biochemistry, the completely revised Third Edition reviews the field from basic science, clinical, epidemiological, and regulatory perspectives. Contributions from top opinion leaders in the field bring together developments in molecular embryology and cell biology as they apply to problems in developmental toxicology. It covers testing of pharmaceutical and environmental agents and interpretation of developmental toxicology data, highlighting mathematical and statistical techniques, as well as the effects of toxic exposure on the functional development of various organs. The relationship between maternal and developmental toxicology is examined, in addition to current techniques for studying chemical disposition, metabolism, and placental transfer. Close attention is given to the regulatory aspects of testing and risk assessment. Pre- and postconceptional clinical care and genetic factors in clinical developmental toxicology are also discussed. Key topics include:
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