| Translational Pain Research: From Mouse to Man Contributor(s): Kruger, Lawrence (Editor), Light, Alan R. (Editor) |
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ISBN: 1439812098 ISBN-13: 9781439812099 Publisher: CRC Press OUR PRICE: $237.50 Product Type: Hardcover - Other Formats Published: November 2009 Annotation: The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, this book examines rodent models for pain associated with bone cancer, osteoarthritis, and cardiac episodes. It covers the cloning of highly specific receptors and the analysis of modular molecular mechanisms relevant to painful neuropathies, while also considering the bearing of this trend toward translational research on the commercial pharmaceutical establishment. |
| Additional Information |
| BISAC Categories: - Medical | Neuroscience - Medical | Diseases - Medical | Research |
| Dewey: 616.047 |
| LCCN: 2009039338 |
| Series: Frontiers in Neuroscience |
| Physical Information: 1" H x 6.2" W x 9.3" (1.65 lbs) 456 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes. Distinguished Team of International Contributors In addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on:
This sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences. |