Actin-Binding Proteins and Disease Contributor(s): Dos Remedios, Cris (Editor), Chhabra, Deepak (Editor) |
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ISBN: 1441924531 ISBN-13: 9781441924537 Publisher: Springer OUR PRICE: $208.99 Product Type: Paperback - Other Formats Published: November 2010 |
Additional Information |
BISAC Categories: - Science | Life Sciences - Biochemistry - Science | Life Sciences - Cell Biology - Science | Life Sciences - Molecular Biology |
Dewey: 571.6 |
Series: Protein Reviews |
Physical Information: 0.79" H x 9.21" W x 6.14" (1.18 lbs) 348 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Actin is a ubiquitous protein present in high concentrations in virtually all cells. It's assembly and disassembly is modulated by more than 100 actin-binding proteins. These interactions are essential for a variety of important cellular processes including cell division, gene expression and motility. There are scattered reports in the published literature citing relationships between actin, actin-binding proteins and disease. This volume brings this information together for the first time, with a focus on human disorders. This volume is relevant to a wide readership including cell biologists interested in understanding how structural and functional changes in proteins impact on the organism as a whole. Additionally, clinicians will be interested because the book explains the role of cytoskeletal proteins in various diseases, including cancer and immune system disorders. |