| Mechanisms of Lymphocyte Activation and Immune Regulation VIII: Autoimmunity 2000 and Beyond Softcover Repri Edition Contributor(s): Gupta, Sudhir (Editor) |
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ISBN: 1461354587 ISBN-13: 9781461354581 Publisher: Springer OUR PRICE: $103.55 Product Type: Paperback - Other Formats Published: September 2012 |
| Additional Information |
| BISAC Categories: - Medical | Immunology - Science | Life Sciences - Biophysics - Science | Life Sciences - Microbiology |
| Dewey: 616.079 |
| Series: Advances in Experimental Medicine and Biology |
| Physical Information: 0.32" H x 6.14" W x 9.21" (0.48 lbs) 136 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists. |