Neurobiology of Essential Fatty Acids Softcover Repri Edition Contributor(s): Bazan, Nicolas G. (Editor), Murphy, Mary G. (Editor), Toffano, Gino (Editor) |
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ISBN: 1461365155 ISBN-13: 9781461365150 Publisher: Springer OUR PRICE: $52.24 Product Type: Paperback Published: October 2012 |
Additional Information |
BISAC Categories: - Science | Life Sciences - Biochemistry - Science | Life Sciences - Botany - Medical | Neuroscience |
Dewey: 571.31 |
Series: Advances in Experimental Medicine and Biology |
Physical Information: 444 pages |
Descriptions, Reviews, Etc. |
Publisher Description: It is increasingly evident that polyunsaturated fatty acids (PUFA), which in the past were often believed to be mere components of cellular membranes of neural tissue, are actually major determinants of the functional properties of neural cells and are intimately involved in brain disease processes. The two families of PUF A, which are derived from the essential polyenes, linoleic (18:26) and a-linolenic (18:33) acids, constitute a major proportion (-30%) of the total fatty acids esterified to brain phospholipids. Each family is distributed in membranes in a highly specific manner with respect to brain region, cell type, and position within each of the phosphoglycerides. Unlike their behavior in other organs, the PUF A components of brain turn over slowly and are relatively resistant to dietary modification. Their unique distribution and stability suggest that they play an important role in determining the functional properties of neural cells. However, until recently very little was known regarding the precise nature of their involvement. |