| Biology and Physiology of the Blood-Brain Barrier: Transport, Cellular Interactions, and Brain Pathologies 1996 Edition Contributor(s): Couraud, Pierre-Olivier (Editor), Scherman, Daniel (Editor) |
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ISBN: 1475794916 ISBN-13: 9781475794915 Publisher: Springer OUR PRICE: $208.99 Product Type: Paperback - Other Formats Published: May 2013 |
| Additional Information |
| BISAC Categories: - Medical | Neurology - Medical | Surgery - Neurosurgery - Medical | Pathology |
| Dewey: 571.1 |
| Series: Advances in Behavioral Biology |
| Physical Information: 0.83" H x 7" W x 10" (1.54 lbs) 388 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: The endothelial cells of the cerebral vasculature constitute, together with perivascular elements (astrocytes, pcricytes, basement membrane), the blood-brain barrier (BBB), which strictly limits and specifically controls the exchanges between the blood and the cerebral extracellular spacc.The existence of such a physical, enzymatic, and active barrier isolating the central nervous system has broad physiological, biological, pharmacological, and patho- logical consequences, most of which are not yet fully elucidated. The Cerebral Vascular Biology conference (CVB '95) was organized and held at the "Carre des Sciences" in Paris on July I 0-12, 1995. Like the CVB '92 conference held in Duluth, Minnesota, three years ago, the objectives were to provide a forum for presentation of the most recent progresses and to stimulate discussions in the ticld of the biology, physiology. and pathology of the blood-brain barrier. The Paris conference gathered more than 50 participants. including investigators in basic neuroscience, physicians. and stu- dents, who actively contributed to the scientific program by their oral or poster presentations. This volume contains a collection of short articles that summarize most of the new data that were presented at the conference. Six thematic parts focus on physiological transports. drug delivery, multidrug resistance P-glycoprotein, signal transduction at the BBB. interactions between the immune system and the cerebral endothelial cells, and the blood-brain barrier-related pathologies in the central nervous system. In addition, two introductory articles present new insights in the rapidly evolving topics of cerebral angiogenesis and gene transfer to the brain. |