Metabolic Network Reconstruction and Modeling: Methods and Protocols [With Online Access] 2018 Edition Contributor(s): Fondi, Marco (Editor) |
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ISBN: 1493975277 ISBN-13: 9781493975273 Publisher: Humana OUR PRICE: $151.99 Product Type: Hardcover Published: December 2017 |
Additional Information |
BISAC Categories: - Science | Life Sciences - Molecular Biology |
Dewey: 571.6 |
Series: Methods in Molecular Biology |
Physical Information: 1.14" H x 7.2" W x 10.28" (2.34 lbs) 410 pages |
Descriptions, Reviews, Etc. |
Publisher Description: This volume looks at the latest methodologies used to study cellular metabolism with in silico approaches. The chapters in this book are divided into 3 parts: part I discusses tools and methods used for metabolic reconstructions and basic constraint-based metabolic modeling (CBMM); Part II explores protocols for the generation of experimental data for metabolic reconstruction and modeling, including transcriptomics, proteomics, and mutant generations; and Part III cover advanced techniques for quantitative modeling of cellular metabolism, including dynamic Flux Balance Analysis and multi-objective optimization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Metabolic Network Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM. |