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Microbiology and Aging: Clinical Manifestations 2009 Edition
Contributor(s): Percival, Steven L. (Editor)
ISBN: 1588296407     ISBN-13: 9781588296405
Publisher: Humana
OUR PRICE:   $161.49  
Product Type: Hardcover - Other Formats
Published: December 2008
Qty:
Additional Information
BISAC Categories:
- Medical | Microbiology
Dewey: 571.878
LCCN: 2008940880
Physical Information: 0.9" H x 6.1" W x 9.3" (1.45 lbs) 348 pages
 
Descriptions, Reviews, Etc.
Publisher Description:
Theworld spopulationisestimatedtoreach8. 9billionby2050with370million peopleof80yearsofageorolder. Ageingisanincurablediseaseandde?nedasthe deregulationofbiochemicalprocessesimportantforlife, butforthepurposeof this book, ageing is better de?ned as the biological process of growing older. Ageingispartofnaturalhumandevelopment. Asyouwillseethroughoutthisbook, themicrobiologicalburdenonthehostis enormousandclinicallysigni?cant, andwillundoubtedlyhavearoletoplayinthe ageing process. As humans are living longer, there is a greater propensity to infection. This risk is substantially heightened in elderly individuals who are predisposedtoinfection. Whiletheprocessofageinganditseffectsonthehost s microbiology are poorly documented and researched, data obtained from gut studieshaveshownthatmicrobiologicalchangestakeplaceovertimesuggesting signi?cancetothehost. Dothemicrobiologicalchangesthatoccurwithinandupon thehostin?uencetheprocessofageingorisitthebiologicalchangesofthehost thataffectsthemicrobiology?Doesthisthereforeaffectourpropensitytodisease? Asthehost smicrobiologychangeswithageing, isthissigni?cantlybene?cialor severelydetrimentaltothehost?Aretherewaysofenhancinglifeexpectancyby reducingcertainbacteriafromproliferatingorconverselybyenhancingthesurvival ofbene?cialbacteria? Thisbookconsidersthemicrobiologyofthehostindifferentregionsofthebody andhowthesevaryinthedifferentagegroups. Chapter1ofthebookfocuseson ageingtheorieswithChap. 2consideringthehumanindigenous?oraandhowthis isaffectedduringageing. Chapter3highlightsthemaininfectionsassociatedwith anelderlypopulation, whileChap. 4reviewstheprocessofskinageingandits associatedmicrobiology. Chapter5reviewstheageinglungandChap. 6reviews in?uenzaintheelderly. Chapter7highlightsthechangesthatoccurintheoral micro?ora and host defences with advanced age with Chap. 8 reviewing the in?uenceofthegutmicrobiotawithageing. Chapter8focusesonthegutandits associatedimmunity. Theremainingfourchaptersofthebookconsiderclostridium andtheageinggut, Helicobacterpyloriandthehygienehypothesisandthebene?ts of probiotics. The microbiology theory of autism in children is reviewed in vii viii Preface Chap. 13. The?nalchapterofthebookexamineshowthebene?cialmicrobiology ofthehostleadstohumandecomposition. Thisbookencompassesacollectionofreviewsthathighlightthesigni?canceof andthecrucialrolethatmicroorganismsplayinthehumanlifecycle. Flintshire, UK StevenL. Percival Contents 1 AgeingTheories, DiseasesandMicroorganisms. . . . . . . . . . . . . . . . . . . . . . . . . 1 StevenL. Percival 2 IndigenousMicrobiotaandAssociationwiththeHost. . . . . . . . . . . . . . . . . 15 JohnG. ThomasandStevenL. Percival 3 InfectionsintheElderly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 KnutOhlsen, SvitlanaKozytska, andUdoLorenz 4 SkinAgingandMicrobiology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 LeslieBaumann, EdmundWeisberg, andStevenL. Percival 5 LungInfectionsandAging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 SameerK. MathurandKeithC. Meyer 6 In?uenzaintheElderly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 CaterinaHatzifotiandAndrewWilliamHeath 7 ChangesinOralMicro?oraandHostDefences withAdvancedAge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131 RimondiaS. Percival 8 In?uenceoftheGutMicrobiotawithAgeing. . . . . . . . . . . . . . . . . . . . . . . . . 153 EileenMurphy, CarolineMurphy, andLiamO Mahony 9 AGutReaction: AgingAffectsGut-AssociatedImmunity . . . . . . . . . . 175 JosephF. AlbrightandJuliaW. Albright 10 ClostridiumandTheAgeingGut. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223 SarahConnorandStevenL. Percival ix x Contents 11 TheSigni?canceofHelicobacterPyloriAcquisition andtheHygieneHypothesis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 StevenL. Percival 12 ProbioticsandtheAgeingGut. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275 StevenL. Percival 13 MicrobiologicalTheoryofAutisminChildhood . . . . . . . . . . . . . . . . . . . . . 291 StevenL. Percival 14 DecompositionofHumanRemains. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313 RobertC. Janaway, StevenL. Percival, andAndrewS. Wilson Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 335 Contributors JosephF. Albright, PhD Departmentof Microbiology, Immunology and Tropical Medicine, The George WashingtonUniversitySchoolofMedicine, Washington, DC, USA JuliaW. Albright, PhD Departmentof Microbiology, Immunology and Tropical Medicine, The George WashingtonUniversitySchoolofMedicine, Washington, DC, USA LeslieBaumann, MD UniversityofMiamiCosmeticCenter, MiamiBeach, FL, USA SarahConnor, MSc DepartmentofMicrobiology, LeedsGeneralIn?rmary, Leeds, UK CaterinaHatzifoti, PhD UniversityofShef?eldMedicalSchool, BeechHillRoad, Shef?eld, UK AndrewW. Heath, PhD UniversityofShef?eldMedicalSchool, BeechHillR