| Transforming Growth Factor-Beta in Cancer Therapy, Volume I: Basic and Clinical Biology 2008 Edition Contributor(s): Jakowlew, Sonia B. (Editor), Sporn, M. B. (Foreword by) |
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ISBN: 1588297144 ISBN-13: 9781588297143 Publisher: Humana OUR PRICE: $208.99 Product Type: Hardcover - Other Formats Published: February 2008 Annotation: Transforming Growth Factor- ?? in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ?? (TGF- ??) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. Part I presents basic concepts of transforming growth factor- ?? signaling in normal physiology and cancer pathobiology. Part II investigates transforming growth factor- ?? superfamily members in normal and tumor biology. The final part details transforming growth factor- ?? in inflammation and fibrosis. This volume??'s companion, Cancer Treatment in Therapy, examines transforming growth factor- ?? in other developing and advanced cancers and methods of treatment and therapy. Together, Transforming Growth Factor- ?? in Cancer Therapy, Vols. 1 and 2, provide researchers and clinicians a comprehensive and cutting-edge reference for the findings about the role of transforming growth factor- ?? in biology and cancer treatment. |
| Additional Information |
| BISAC Categories: - Medical | Oncology - General - Medical | Pharmacology |
| Dewey: 571.6 |
| Series: Cancer Drug Discovery and Development (Unnumbered) |
| Physical Information: 1.27" H x 7.5" W x 10.15" (3.73 lbs) 735 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that is fundamental to understanding the roleofTGF- in the pathogenesis, prevention, and treatment of cancer. It is not even 25 years sinceTGF- was first isolated and characterized as a dimeric pep- tide from both human and bovine sources (1-3), but the entire fieldofTGF- research has grown and expanded so that it is now a central theme in all of cell biology. There is almost no tissue or organ in the mammalian body in whichTGF- does not playa central role in embryonic differentiation or in adult function, and furthermore, malfunction of the normal physiologyofTGF- can have disastrous consequences in almost all ofthese sites. Therefore, the present comprehensive review of so many aspects ofTGF- function is a most welcome attempt to bring together a huge body of experimental data that is of the utmost importance in the field of oncology. |