| The GABA Receptors Contributor(s): Enna, Salvatore J. (Editor), Möhler, Hanns (Editor) |
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ISBN: 1588298132 ISBN-13: 9781588298133 Publisher: Humana OUR PRICE: $208.99 Product Type: Hardcover - Other Formats Published: July 2007 Annotation: "The Gaba Receptors, Third Edition," presents a critical appraisal of our current understanding of the molecular, behavioral, biochemical, clinical, and pharmacological properties of GABA receptors. Emphasis is placed on exploring cutting-edge findings on the structural properties of receptor sites, mechanisms of receptor expression, chemical agents that differentiate receptor subtypes, and phenotypes displayed by GABA receptor null mice. Chapters in this updated and expanded edition examine such topics as GABA receptor subtypes, trafficking postsynaptic GABA receptors, GABA receptor mutations associated with idiopathic generalized epilepsies and febrile seizures, and GABA receptors as a potential therapeutic target. |
| Additional Information |
| BISAC Categories: - Medical | Pain Medicine - Medical | Neurology - Medical | Neuroscience |
| Dewey: 615.78 |
| LCCN: 2007930261 |
| Series: Receptors |
| Physical Information: 0.76" H x 6.59" W x 9.22" (1.49 lbs) 325 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: This volume is the third edition of a monograph series that was first published in 1983. The demand for this work is a testament to the impact of studies on -aminobutyric acid (GABA) receptors on the basic understanding of synaptic transmission and on defining the clinical importance of the neurotransmitter system. Chronicled in The GABA Receptors, Third Edition, are the advances made in understanding the molecular and pharmacological properties of GABA A and GABA receptors since the topic was last reviewed in 1996. Particular B emphasis is placed on describing the assembly, structure, and function of GABA B sites, the first heterodimeric G protein-coupled receptors identified in vivo. In addition, there are reports dealing with the subunit composition, trafficking, and pharmacological selectivity of GABA receptors. Aside from providing A insights into the fundamental properties of ligand-gated ion channels and second messenger systems, the findings detailed in this work point the way for developing novel therapeutics capable of more selectively manipulating these transmitter sites. |