| Platinum-Based Drugs in Cancer Therapy Contributor(s): Kelland, Lloyd R. (Editor), Farrell, Nicholas P. (Editor) |
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ISBN: 1617370916 ISBN-13: 9781617370915 Publisher: Humana OUR PRICE: $113.99 Product Type: Paperback - Other Formats Published: December 2010 |
| Additional Information |
| BISAC Categories: - Medical | Chemotherapy - Medical | Oncology - General - Medical | Pharmacology |
| Dewey: 616.994 |
| Series: Cancer Drug Discovery & Development |
| Physical Information: 0.74" H x 6.14" W x 9.21" (1.10 lbs) 341 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair and replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs. |