| Transforming Growth Factor-Beta in Cancer Therapy, Volume I: Basic and Clinical Biology Contributor(s): Jakowlew, Sonia B. (Editor), Sporn, M. B. (Foreword by) |
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ISBN: 161737735X ISBN-13: 9781617377358 Publisher: Humana OUR PRICE: $237.49 Product Type: Paperback - Other Formats Published: November 2010 |
| Additional Information |
| BISAC Categories: - Medical | Oncology - General - Medical | Pharmacology - Science | Life Sciences - Cell Biology |
| Dewey: 571.6 |
| Series: Cancer Drug Discovery & Development |
| Physical Information: 1.51" H x 7" W x 10" (2.85 lbs) 735 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that is fundamental to understanding the roleofTGF- in the pathogenesis, prevention, and treatment of cancer. It is not even 25 years sinceTGF- was first isolated and characterized as a dimeric pep- tide from both human and bovine sources (1-3), but the entire fieldofTGF- research has grown and expanded so that it is now a central theme in all of cell biology. There is almost no tissue or organ in the mammalian body in whichTGF- does not playa central role in embryonic differentiation or in adult function, and furthermore, malfunction of the normal physiologyofTGF- can have disastrous consequences in almost all ofthese sites. Therefore, the present comprehensive review of so many aspects ofTGF- function is a most welcome attempt to bring together a huge body of experimental data that is of the utmost importance in the field of oncology. |