| Leishmania: Current Biology and Control Contributor(s): Adak, Subrata (Editor), Datta, Rupak (Editor) |
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ISBN: 1908230525 ISBN-13: 9781908230522 Publisher: Caister Academic Press Limited OUR PRICE: $237.50 Product Type: Hardcover - Other Formats Published: January 2015 |
| Additional Information |
| BISAC Categories: - Medical | Parasitology - Science | Life Sciences - Microbiology - Medical | Infectious Diseases |
| Dewey: 593 |
| Physical Information: 0.81" H x 6.69" W x 9.61" (1.66 lbs) 254 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Every year, with an estimated 1.3 million new cases and more than 20,000 deaths, Leishmaniasis continues to be a menace in countries across the globe. With the absence of an anti-Leishmania vaccine - along with the toxicity of current anti-parasite drugs and coupled with the rapid emergence of drug resistant Leishmania strains - there remains significant challenges for disease control. This has spurred a plethora of research initiatives into parasite biology, parasite-host interaction, mechanisms of disease pathogenesis, drug development, and the molecular mechanism of drug resistance. Insights obtained from various studies are essential for the development of novel anti-Leishmania treatment strategies. In this timely book, respected Leishmania experts distil important current research, highlighting the most insightful discoveries in the field. Topics covered include: modulation of host miRNA * heat shock proteins * iron in the Leishmania-macrophage interaction * oxidative and nitrosative stress response * cell death * strategies for immune evasion * STAT signaling * parasite modulation of toll-like receptors in macrophages * T cells in Leishmania infection * vaccine biology * inhibitors of Leishmania DNA topoisomerases * mechanism of drug resistance in visceral Leishmaniasis. The book is an essential text for everyone in the Leishmania community and is recommended for researchers working in related fields. |