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The contributions included in the volume are drawn from presentations at ODS2019 - International Conference on Optimization and Decision Science, which was the 49th annual meeting of the Italian Operations Research Society (AIRO) held at Genoa, Italy, on 4-7 September 2019. This book presents very recent results in the field of Optimization and Decision Science. While the book is addressed primarily to the Operations Research (OR) community, the interdisciplinary contents ensure that it will also be of very high interest for scholars and researchers from many scientific disciplines, including computer sciences, economics, mathematics, and engineering. Operations Research is known as the discipline of optimization applied to real-world problems and to complex decision-making fields. The focus is on mathematical and quantitative methods aimed at determining optimal or near-optimal solutions in acceptable computation times. This volume not only presents theoretical results but also covers real industrial applications, making it interesting for practitioners facing decision problems in logistics, manufacturing production, and services. Readers will accordingly find innovative ideas from both a methodological and an applied perspective.