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GABA and Sleep: Molecular, Functional and Clinical Aspects
Contributor(s): Monti, Jaime M. (Editor), Pandi-Perumal, Seithikurippu Ratnas (Editor), Möhler, Hanns (Editor)
ISBN: 3034602251     ISBN-13: 9783034602259
Publisher: Springer
OUR PRICE:   $208.99  
Product Type: Hardcover - Other Formats
Published: September 2010
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Additional Information
BISAC Categories:
- Science | Life Sciences - Human Anatomy & Physiology
Dewey: 612.82
Physical Information: 1.2" H x 6.1" W x 9.2" (1.85 lbs) 486 pages
 
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Publisher Description:

GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. The GABA system is, therefore, of prime clinical relevance for the therapy of insomnia.

The focus of this volume is on the neuropsychopharmacology and the clinical impact of the GABA system in regulating sleep and wakefulness. It presents molecular, neuropharmacological, systems-biological and clinical approaches to the understanding of the mechanism of action of GABA and GABAergic drugs. It also explores the role of GABA in the basic drives that affect sleep, and the influences that adapt sleep and wakefulness to external events.