Progress in Drug Research Softcover Repri Edition Contributor(s): Wang, Q. May (Contribution by), Heinz, Beverly A. (Contribution by), Glasel, Jay A. (Contribution by) |
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ISBN: 3034895445 ISBN-13: 9783034895446 Publisher: Birkhauser OUR PRICE: $52.24 Product Type: Paperback Published: October 2012 |
Additional Information |
BISAC Categories: - Gardening - Medical |
Dewey: 610 |
Series: Progress in Drug Research |
Physical Information: 0.72" H x 7" W x 10" (1.33 lbs) 336 pages |
Descriptions, Reviews, Etc. |
Publisher Description: Hepatitis C virus (HCV) was first identified in 1989 as the etiologic agent of non-A, non-B hepatitis 1] and is currently recognized as the leading cause of chronic liver disease worldwide. In contrast to hepatitis B virus infection, in which only about 5% of adult infections become chronic, more than 80% of HCV-infected patients develop chronic hepatitis. Moreover, 20-50% of those persistently infected with HCV will develop liver cirrhosis and hepatocellu- lar carcinoma (HCC) 2]. It is estimated that there are 10,000 deaths in the USA per year due to chronic liver failure or HCC 3]. In addition, HCV dis- 25-50% of all liver transplants in US centers, and the ease is responsible for recurrence of HCV infection following liver transplantation is universal 4]. Typically, HCV disease emerges after a 10-20 year period during which symp- toms, if they exist at all, are mild and non-specific. Although the prevalence varies greatly among different countries, it has been estimated that up to 170 million people (3% of the world's population), are infected with HCV 5]. A recent study in the USA found that 65% of all HCV-infected persons are 30 to 49 years old 6]. |