| Stereoselective Syntheses of Tetrahydropyrans: Applications to the Synthesis of (+)-Leucascandrolide A, (+)-Dactylolide and (±)-Diospongin a 2014 Edition Contributor(s): Lee, Kiyoun (Author) |
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ISBN: 3319044613 ISBN-13: 9783319044613 Publisher: Springer OUR PRICE: $104.49 Product Type: Hardcover - Other Formats Published: March 2014 |
| Additional Information |
| BISAC Categories: - Science | Chemistry - Organic - Medical | Pharmacy - Science | Chemistry - Industrial & Technical |
| Dewey: 547 |
| Series: Springer Theses |
| Physical Information: 0.7" H x 6.2" W x 9.2" (0.95 lbs) 184 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP). Readers gain insight into the new methods Lee employs for the synthesis of biologically interesting natural products including (+)-leucascandrolide A, (+)-dactylolide, and ( )diospongin A. The reactions Lee investigates are applicable to a broad range of substrates and proceed with excellent stereoselectivity. Moreover, the methodologies allow the synthesis of a wide range of THP-containing compounds. The development of reactions, such as those discussed by Lee, has the potential to impact natural product synthesis, pharmaceutical development and chemical biology. |