| Protein-Protein Interactions as New Drug Targets 2008 Edition Contributor(s): Klussmann, Enno (Editor), Scott, John (Editor) |
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ISBN: 3540728422 ISBN-13: 9783540728429 Publisher: Springer OUR PRICE: $313.49 Product Type: Hardcover - Other Formats Published: June 2008 |
| Additional Information |
| BISAC Categories: - Medical | Pharmacology - Medical | Biochemistry - Science | Life Sciences - Molecular Biology |
| Dewey: 571.6 |
| Series: Handbook of Experimental Pharmacology |
| Physical Information: 0.9" H x 6.3" W x 9.3" (1.85 lbs) 512 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions. This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted. |