| Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I Contributor(s): Hacker, J. (Editor), Kaper, J. B. (Editor) |
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ISBN: 3642076564 ISBN-13: 9783642076565 Publisher: Springer OUR PRICE: $161.49 Product Type: Paperback - Other Formats Published: December 2010 |
| Additional Information |
| BISAC Categories: - Science | Life Sciences - Microbiology - Science | Life Sciences - Genetics & Genomics - Medical | Immunology |
| Dewey: 616.014 |
| Series: Current Topics in Microbiology and Immmunology |
| Physical Information: 234 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well due to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements. |
