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The Double [3]2] Photocycloaddition Reaction 2011 Edition
Contributor(s): Woolford, Jason A. (Author)
ISBN: 3642228593     ISBN-13: 9783642228599
Publisher: Springer
OUR PRICE:   $104.49  
Product Type: Hardcover - Other Formats
Published: August 2011
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Additional Information
BISAC Categories:
- Science | Chemistry - Analytic
- Science | Chemistry - Organic
- Science | Chemistry - Clinical
Dewey: 541.39
Series: Springer Theses
Physical Information: 0.5" H x 6.14" W x 9.21" (1.01 lbs) 184 pages
 
Descriptions, Reviews, Etc.
Publisher Description:
Jason Woolford's thesis describes for the first time, a double 3]2] photocycloaddition of alkenes onto aromatic rings. Modern synthetic chemistry relies on the ability of researchers to uncover new and more efficient ways of creating highly complex structures. This work describes a novel, environmentally friendly photochemical step that converts in one pot, trivial starting materials into otherwise difficult to construct fenstrane frameworks. The rigid cores of these frameworks have significant potential in drug design. Moreover, the novelty of this work overtakes many other methods for the creation of chiral centres. No less than seven chiral centres are created in the photochemical step together with the formation of four carbon-carbon bonds and multifused rings. Jason's innovative work has been the subject of several publications in peer-reviewed journals.