| Protein Quality Control in Neurodegenerative Diseases 2013 Edition Contributor(s): Morimoto, Richard I. (Editor), Christen, Yves (Editor) |
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ISBN: 3642447066 ISBN-13: 9783642447068 Publisher: Springer OUR PRICE: $161.49 Product Type: Paperback - Other Formats Published: January 2015 |
| Additional Information |
| BISAC Categories: - Medical | Neuroscience - Science | Life Sciences - Molecular Biology - Medical | Anatomy |
| Dewey: 611.018 |
| Series: Research and Perspectives in Alzheimer's Disease |
| Physical Information: 0.32" H x 6.14" W x 9.21" (0.48 lbs) 136 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation. |