| Chronopharmaceutical drug delivery of Salbutamol Sulphate Contributor(s): Patel, Priti (Author), Doshi, Ravi (Author), Patel, Kanu (Author) |
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ISBN: 3659137766 ISBN-13: 9783659137761 Publisher: LAP Lambert Academic Publishing OUR PRICE: $60.53 Product Type: Paperback Published: May 2012 |
| Additional Information |
| BISAC Categories: - Medical | Pharmacology |
| Physical Information: 0.29" H x 6" W x 9" (0.42 lbs) 124 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: The present research work is to design and evaluate an oral time dependent, pulsatile drug delivery system containing Salbutamol Sulphate, which can be targeted to time dependent manner, to modulate the drug level in synchrony with the circadian rhythm of nocturnal asthma. A time dependent pulsatile dosage form was developed by using a various grade of HPC in compressed coated layer. A pulsatile 'Tablet in Tablet' dosage form, taken at bed time with a programmed start of drug release early in morning hours, can prevent a sharp increase in the incidence of asthmatic attacks, during the early morning hours (nocturnal asthma), a time when the risk of asthmatic attacks is the greatest. |
