| Glycoproteins and Human Disease Softcover Repri Edition Contributor(s): Brockhausen, Inka (Author), Kuhns, William (Author) |
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ISBN: 366221962X ISBN-13: 9783662219621 Publisher: Springer OUR PRICE: $104.49 Product Type: Paperback - Other Formats Published: April 2014 |
| Additional Information |
| BISAC Categories: - Medical | Nutrition - Medical | Biochemistry - Science | Life Sciences - Molecular Biology |
| Dewey: 616.399 |
| Series: Medical Intelligence Unit (Unnumbered) |
| Physical Information: 0.55" H x 7" W x 10" (1.01 lbs) 242 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Diverse alterations of glycosylation occur in diseases such as cancer, metastasis, leukemia, inflammatory and other diseases. The glycosylation abnormalities found in disease are the result of complex rearrangements of the oligosaccharide assembly by glycosyltransferases. This volume reviews several mechanisms that may underly the extremely complex alterations in disease. Disease specific glycosylation may contribute to the disease process by altering cellular functions, or may be exploited therapeutically. Specific therapy may be aimed at correcting glycosylation abnormalities based on knowledge of the mechanisms leading to the disease phenotype and the three-dimensional interactions between carbohydrates and carbohydrate-binding molecules. |